Product Details-
| Composition | Calcium Dobesilate 500mg |
|---|---|
| Dosage | CAPSULE |
| Packing Size | 10×10 |
| Packing | Blister |
Dobefine 500 is a specialized formulation containing Calcium Dobesilate Monohydrate 500 mg, designed to treat and manage microvascular complications, especially in diabetic patients. Used extensively in the management of diabetic retinopathy, chronic venous insufficiency, and hemorrhoids, Dobefine 500 enhances capillary function, reduces blood viscosity, and provides potent antioxidant support.
If you’re looking for a therapeutic solution that protects blood vessels, improves microcirculation, and tackles oxidative stress, Dobefine 500 is the gold-standard choice recommended by vascular specialists and diabetologists alike.
Each film-coated tablet of Dobefine 500 contains:
Calcium Dobesilate Monohydrate 500 mg
Dobefine 500 acts on the endothelial layer of blood vessels, stabilizing and strengthening capillary walls. It:
Reduces capillary permeability and fragility
Improves microcirculatory flow
Inhibits platelet aggregation
Lowers blood viscosity
Provides antioxidant protection to blood vessels
By working at the root of microvascular damage, Dobefine 500 helps delay the progression of diseases like diabetic retinopathy and chronic venous disorders.
Dobefine 500 is widely prescribed to prevent or slow the progression of retinal damage caused by long-term diabetes. It:
Reduces retinal edema
Improves capillary resistance
Enhances retinal oxygenation
It’s most effective in non-proliferative diabetic retinopathy and as an adjunct in proliferative stages.
Patients with leg pain, swelling, varicose veins, or heaviness benefit from Dobefine 500 as it improves venous tone and relieves inflammation.
By reducing vascular congestion and inflammation in the rectal veins, Dobefine 500 helps:
Alleviate bleeding
Relieve pain and swelling
Promote faster healing
Dobefine 500 strengthens capillaries and improves lymphatic drainage, providing relief in lymphedema, bruising, and vascular fragility.
Dobefine 500 reinforces blood vessel walls, making them less prone to leakage, rupture, and damage—especially critical in diabetic patients.
Calcium dobesilate in Dobefine 500 reduces oxidative stress markers and inhibits lipid peroxidation, which slows down tissue damage in microvascular beds.
By reducing blood viscosity and enhancing microcirculation, Dobefine 500 supports better oxygen delivery to tissues.
Unlike steroids or NSAIDs, Dobefine 500 offers long-term safety for chronic use in diabetic or vascular patients.
It not only relieves symptoms (e.g., swelling, heaviness, vision blur) but also delays disease progression in chronic vascular disorders.
Adults: 500 mg to 1000 mg daily in divided doses
For Diabetic Retinopathy: 500 mg twice daily
For CVI or Hemorrhoids: 500 mg once or twice daily based on severity
Always follow your healthcare provider’s guidance for exact dosing.
Take Dobefine 500 with meals
Swallow whole with water
Avoid crushing or chewing
Hypersensitivity to calcium dobesilate
Active bleeding disorders without physician supervision
Pregnancy (unless clearly needed)
Severe liver or kidney impairment
While Dobefine 500 is generally safe, it should be used cautiously with:
Anticoagulants (monitor INR)
Antiplatelet agents
Other drugs affecting blood viscosity
Always inform your doctor of all medications being taken.
Nausea or upset stomach
Skin rash (mild and reversible)
Headache
Diarrhea
Agranulocytosis (extremely rare)
Hypersensitivity reactions
Fever
Most side effects resolve on their own. However, contact your physician if symptoms persist or worsen.
Store Dobefine 500 at room temperature (below 25°C)
Keep away from moisture and sunlight
Keep out of reach of children
Do not use if the blister pack is damaged
Calcium dobesilate—the active ingredient in Dobefine 500—has been extensively studied and is included in treatment protocols for diabetic retinopathy across Europe and Asia.
Numerous trials demonstrate its ability to:
Reduce retinal microaneurysms
Decrease vascular leakage
Improve microvascular blood flow
Physicians recommend Dobefine 500 for long-term therapy in patients with diabetes, vascular disorders, and venous insufficiency.
Dobefine 500 tablets available in strips of 10
Hospital packs available for long-term treatment facilities
Dobefine 500 is a prescription-only medication and should be used under medical supervision.
In the modern world of chronic diseases, vascular protection is non-negotiable. Dobefine 500 delivers unmatched benefits for diabetic patients, those with venous insufficiency, and individuals prone to capillary fragility. Its potent antioxidant, anti-inflammatory, and endothelial-stabilizing actions make it a game-changer in vascular therapy.
From protecting your vision to reducing painful swelling in your legs, Dobefine 500 works gently yet powerfully, helping you stay active, healthy, and confident.
Trust Dobefine 500 for superior vascular care with every dose.
