LABECIA 100

LABECIA 100 Tablets

Introduction

LABECIA 100 is a highly effective prescription medication formulated with Labetalol Hydrochloride (100mg), a unique antihypertensive drug that belongs to the class of combined alpha- and beta-adrenergic blocking agents. It is primarily used in the management of high blood pressure (hypertension), helping reduce the risk of severe complications such as heart attack, stroke, and kidney damage. LABECIA 100 is suitable for patients requiring effective and balanced blood pressure control, especially in cases where single-action drugs are insufficient.

Mechanism of Action

Labetalol works by blocking both alpha-1 adrenergic receptors and non-selective beta-adrenergic receptors:

• Alpha-1 blockade: Causes vasodilation, reducing peripheral vascular resistance and lowering blood pressure.

• Beta-blockade: Reduces heart rate, myocardial contractility, and cardiac output, further contributing to blood pressure control.
  This dual mechanism makes LABECIA 100 especially effective for patients with severe or resistant hypertension, as it provides comprehensive control without significant reflex tachycardia.

Indications

LABECIA 100 is indicated for:

• Essential hypertension (primary hypertension)

• Hypertensive emergencies and urgencies (as part of hospital treatment)

• Pregnancy-induced hypertension or pre-eclampsia (under medical supervision)

• Hypertension in patients with angina or other cardiac risk factors

• Secondary hypertension associated with renal or endocrine disorders

Benefits of LABECIA 100

1. Dual Action for Better Control – Targets both alpha and beta receptors, providing comprehensive blood pressure reduction.

2. Rapid Onset – Quickly reduces blood pressure in acute situations.

3. Well-Tolerated – Can be safely used in pregnant women and those with co-existing conditions (with monitoring).

4. Reduces Risk of Cardiovascular Events – Long-term use significantly decreases the risk of heart disease, kidney failure, and stroke.

5. Flexible Dosing – Available in different strengths for easy titration based on patient needs.

Dosage and Administration

• Typical Starting Dose: 100mg twice daily (morning and evening).

• Maintenance Dose: Usually ranges between 200mg and 400mg twice daily.

• Maximum Dose: Up to 2400mg per day in divided doses, depending on severity and response.

• Should be swallowed whole with water, preferably at the same time each day.

• Important: Dosage must be personalized based on a doctor’s prescription.

Side Effects

Common side effects include:

• Fatigue or dizziness

• Nausea or gastrointestinal upset

• Nasal congestion

• Mild scalp tingling
  Less common but serious effects (require immediate medical attention):

• Severe bradycardia (slow heart rate)

• Difficulty breathing (bronchospasm)

• Severe hypotension

• Worsening of heart failure

Precautions

• Avoid sudden discontinuation; tapering is necessary to prevent rebound hypertension.

• Not recommended in patients with severe asthma or chronic obstructive pulmonary disease (COPD) due to beta-blockade effects.

• Caution in patients with liver impairment, heart failure, or bradycardia.

• Monitor blood pressure, heart rate, and liver function regularly.

Drug Interactions

• Other antihypertensives (may enhance BP-lowering effects)

• Insulin or oral hypoglycemics (may mask hypoglycemia symptoms)

• Anesthetics or sedatives (increased hypotensive effects)

• Calcium channel blockers (risk of heart conduction issues)

Storage Guidelines

• Store in a cool, dry place away from direct sunlight.

• Keep out of reach of children.

• Do not use expired tablets.

Why Choose LABECIA 100?

LABECIA 100 is a trusted, evidence-based medication that provides robust blood pressure control. With its unique alpha- and beta-blocking properties, it is particularly effective in cases where conventional antihypertensive medications are insufficient. It is also widely prescribed in pregnancy-induced hypertension, making it a preferred choice for obstetricians and cardiologists.