Product Details-
| Composition | Levetiracetam 1000mg |
|---|---|
| Dosage | TABLET |
| Packing Size | 10×10 |
| Packing | Blister |
Levicip 1000 SR is a sustained-release (SR) formulation of levetiracetam, delivering 1000 mg of the active ingredient designed to provide consistent therapeutic plasma levels over an extended period. This extended-release property allows for convenient once-daily dosing, improving patient adherence and maintaining effective control of various seizure types.
This comprehensive overview will delve into Levicip 1000 SR’s pharmacology, mechanism of action, clinical applications, dosing guidelines, safety profile, drug interactions, and patient outcomes. Whether you are a patient, caregiver, or healthcare professional, this guide offers in-depth knowledge about the benefits and usage of Levicip 1000 SR.
Each tablet of Levicip 1000 SR contains 1000 mg of levetiracetam in a specially designed matrix that ensures gradual release into the bloodstream. This extended-release technology maintains steady plasma drug concentrations, reducing peak-trough fluctuations common with immediate-release formulations.
The formulation includes inert excipients to enhance absorption and gastrointestinal tolerance, minimizing side effects and maximizing patient comfort during long-term therapy.
Levicip 1000 SR’s active component, levetiracetam, binds selectively to synaptic vesicle protein 2A (SV2A), modulating neurotransmitter release and stabilizing neuronal excitability. This unique mechanism interrupts abnormal electrical activity in the brain responsible for seizures without broadly depressing central nervous system function.
By maintaining steady plasma levels, the sustained-release formulation ensures continuous seizure suppression, reducing the risk of breakthrough seizures and improving overall seizure control.
Levicip 1000 SR is approved for the treatment of:
Partial-onset Seizures: As monotherapy or adjunctive therapy in adults and adolescents.
Generalized Tonic-Clonic Seizures: Effective in controlling idiopathic generalized epilepsy.
Myoclonic Seizures: Particularly in juvenile myoclonic epilepsy.
Off-label Neuropathic Pain: Sometimes prescribed for nerve pain conditions.
Its versatility makes Levicip 1000 SR an integral part of modern epilepsy treatment regimens.
Levicip 1000 SR offers the advantage of once-daily dosing, improving compliance:
Starting Dose: Generally initiated at 1000 mg once daily, with adjustment based on clinical response.
Maintenance Dose: Can be titrated up to 3000 mg once daily in divided doses or as directed.
Pediatric Use: Dosage adjustments based on age and weight; consultation with specialists is necessary.
Dose Modifications: Required in patients with renal impairment or elderly populations.
Discontinuation: Gradual tapering is essential to avoid seizure recurrence.
Adherence to dosing instructions is critical for optimal seizure management.
Patients treated with Levicip 1000 SR report:
Sustained Seizure Reduction: Effective control of diverse seizure types with fewer breakthrough episodes.
Improved Adherence: Once-daily dosing simplifies treatment regimens and enhances compliance.
Reduced Side Effects: Steady drug levels minimize peak-related adverse effects such as dizziness or sedation.
Enhanced Daily Functioning: Better seizure control supports improved cognition, mood, and independence.
Better Sleep Quality: Seizure stabilization often leads to improved rest and overall wellbeing.
These benefits contribute significantly to patient safety and lifestyle.
Levicip 1000 SR is generally well tolerated. Common side effects include:
Fatigue and dizziness
Headache
Irritability or mood changes
Gastrointestinal symptoms such as nausea or diarrhea
Somnolence or sleep disturbances
Most adverse effects are mild and often resolve with continued treatment or dose adjustments.
Rare but serious effects to monitor:
Psychiatric symptoms including depression, aggression, or suicidal ideation
Allergic reactions such as rash, swelling, or anaphylaxis
Hematologic abnormalities including leukopenia or thrombocytopenia
Renal impairment necessitating dose adjustments
Immediate medical attention is required if serious symptoms arise.
Levicip 1000 SR is contraindicated in:
Known hypersensitivity to levetiracetam or any formulation components
Patients with severe renal failure without appropriate dose modifications
Precautions are advised for:
Individuals with psychiatric history due to potential mood effects
Pregnant and breastfeeding women, only when benefits outweigh risks
Regular monitoring and clinical evaluation are necessary.
Levicip 1000 SR has minimal drug interactions but caution is needed when co-administered with:
Other antiepileptic medications, which may necessitate dose adjustments
Central nervous system depressants, increasing sedation risk
Hormonal contraceptives, which may have reduced effectiveness
Drugs cleared renally that might affect levetiracetam elimination
Full disclosure of medication history to healthcare providers is essential for safety.
Optimal seizure control with Levicip 1000 SR involves:
Maintaining a healthy, balanced diet
Regular physical activity and stress management
Avoiding seizure triggers such as sleep deprivation, alcohol, and certain medications
Participating in cognitive rehabilitation or counseling when needed
Following a structured daily routine for stability
Such measures enhance medication effectiveness and quality of life.
Store Levicip 1000 SR tablets in a cool, dry place, protected from light and moisture, ideally between 20°C and 25°C. Keep out of reach of children. Dispose of expired or unused medication safely according to local regulations.
How quickly does Levicip 1000 SR work?
Seizure control may begin within the first week; full benefits often appear over several weeks.
Is Levicip 1000 SR addictive?
No, it is not addictive but must be taken consistently to maintain seizure control.
Can I consume alcohol while on Levicip 1000 SR?
Alcohol can increase sedation and seizure risk and should be avoided.
What should I do if I miss a dose?
Take it as soon as you remember unless it’s near the next dose; do not double doses.
Is Levicip 1000 SR safe during pregnancy?
Use only under medical supervision, with a careful assessment of risks and benefits.
Levicip 1000 SR offers a scientifically advanced, patient-friendly solution for managing epilepsy. Its extended-release formulation provides sustained seizure control with the convenience of once-daily dosing, improved tolerability, and minimal drug interactions.
Coupled with lifestyle adaptations and regular medical monitoring, Levicip 1000 SR empowers patients to live fuller, safer lives with fewer seizures and greater independence.
