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ACECOPRO -100

Product Details-

Composition Acebrophylline – 100 mg
Dosage CAPSULE
Packing Size 10×10
Packing Blister

Additional information

Introduction

Acecopro-100 is a pharmaceutical formulation that contains Acebrophylline 100 mg in capsule form. It is primarily prescribed for patients with respiratory disorders such as asthma, chronic obstructive pulmonary disease (COPD), bronchitis, emphysema, and other airway-related conditions. Acebrophylline is a unique drug because it is both a bronchodilator and a mucolytic agent, providing a dual mechanism of action that helps improve airflow while clearing mucus from the respiratory tract. This makes Acecopro-100 a preferred choice in managing chronic respiratory illnesses where both airway obstruction and excessive mucus secretion are present.


Composition and Strength

Each Acecopro-100 capsule contains:

  • Acebrophylline 100 mg

Acebrophylline is a xanthine derivative that combines Ambroxol (a mucolytic agent) and Theophylline-7-acetic acid (a bronchodilator) in a single molecule, offering synergistic effects for patients suffering from chronic respiratory conditions.


Pharmacological Classification

  • Therapeutic Class: Bronchodilator & Mucolytic

  • Drug Category: Xanthine derivative

  • Dosage Form: Oral Capsule

  • Route of Administration: Oral


Mechanism of Action

Acebrophylline works through a dual mechanism:

  1. Bronchodilation:

    • The Theophylline derivative in Acebrophylline inhibits the enzyme phosphodiesterase (PDE), leading to an increase in cyclic AMP (cAMP) levels. This causes relaxation of smooth muscles in the airways, widening them and easing airflow.

    • It also has mild anti-inflammatory properties that help reduce swelling in the bronchial passages.

  2. Mucolytic Action:

    • Ambroxol, a component of Acebrophylline, enhances the production of surfactant, reduces mucus viscosity, and facilitates mucociliary clearance.

    • This action ensures that thick mucus in the respiratory tract becomes thinner and easier to expel, improving breathing efficiency.


Therapeutic Indications

Acecopro-100 is prescribed for:

  • Chronic Obstructive Pulmonary Disease (COPD)

  • Bronchial Asthma

  • Chronic Bronchitis

  • Emphysema

  • Bronchiectasis

  • Allergic Bronchitis

  • Respiratory conditions with mucus overproduction

It is suitable for long-term management of obstructive airway diseases and improves patients’ quality of life by reducing breathlessness, cough, and mucus accumulation.


Dosage and Administration

  • Usual Adult Dose:
    One capsule of Acecopro-100 is usually taken once or twice daily as directed by a physician.

  • Route: Oral, to be swallowed whole with water.

  • Timing: Preferably after meals to minimize gastrointestinal discomfort.

  • Dosage may vary based on the severity of the disease and the patient’s medical history.

  • Important: The capsule should not be chewed or crushed.


Key Benefits of Acecopro-100

  1. Dual Action Formula:

    • Offers both bronchodilation and mucolysis in a single capsule.

  2. Improved Airflow:

    • Relaxes airway muscles and allows easier breathing.

  3. Enhanced Mucus Clearance:

    • Reduces mucus thickness and promotes natural airway clearance.

  4. Anti-inflammatory Properties:

    • Helps reduce airway inflammation, preventing frequent exacerbations.

  5. Convenient Dosing:

    • Taken orally, usually once or twice a day, making it suitable for chronic treatment plans.


Pharmacokinetics

  • Absorption: Rapidly absorbed after oral administration.

  • Distribution: Distributed widely to lung tissues, reaching therapeutic concentrations in the respiratory tract.

  • Metabolism: Metabolized in the liver primarily by CYP enzymes.

  • Elimination: Excreted mainly via urine.

  • Half-life: Approximately 6–8 hours, supporting twice-daily dosing.


Side Effects

While Acecopro-100 is generally well tolerated, some patients may experience mild side effects:

  • Nausea, vomiting

  • Headache, dizziness

  • Gastrointestinal discomfort

  • Heartburn

  • Tremors or palpitations (in sensitive patients)

  • Increased heart rate (rare)


Precautions and Warnings

  • Liver or Kidney Impairment: Dose adjustment may be necessary.

  • Pregnancy and Lactation: Use only if prescribed by a doctor.

  • Cardiac Patients: Caution is advised in patients with heart conditions due to xanthine derivatives’ stimulant effects.

  • Drug Interactions: Avoid concurrent use with other xanthine derivatives, certain antibiotics, or anti-seizure medications without medical supervision.


Contraindications

Acecopro-100 should not be used in:

  • Patients allergic to Acebrophylline or similar drugs.

  • Patients with severe cardiac arrhythmias.

  • Uncontrolled hypertension.

  • History of peptic ulcers (due to xanthine component).


Storage Instructions

  • Store in a cool, dry place below 25°C.

  • Keep away from direct sunlight and moisture.

  • Keep out of reach of children.


Packaging Information

Acecopro-100 is available in strips of capsules that are blister-packed for protection against moisture and contamination.


Why Choose Acecopro-100?

  • A clinically proven medication for effective management of chronic respiratory disorders.

  • Provides comprehensive relief by opening up airways and reducing mucus buildup.

  • Well-tolerated with minimal side effects when taken under medical supervision.

  • Offers a balanced therapeutic approach by addressing both bronchospasm and mucus production simultaneously.


Patient Counseling Information

  • Take the capsule at the same time each day for consistent results.

  • Do not exceed the recommended dosage.

  • Avoid alcohol and smoking, as these may worsen respiratory conditions.

  • Stay hydrated to aid mucus clearance.

  • Consult a doctor immediately if you experience severe side effects like chest pain, irregular heartbeat, or allergic reactions.


Conclusion

Acecopro-100 (Acebrophylline 100 mg capsule) is an advanced respiratory care medication that offers dual benefits of bronchodilation and mucolysis. It is highly effective for patients with chronic obstructive airway diseases, asthma, bronchitis, and emphysema. The formulation is well-researched and provides long-lasting relief from symptoms such as breathlessness, wheezing, and persistent cough. Its convenient capsule form ensures easy administration and better compliance for long-term therapy.

By combining airway relaxation with mucus clearance, Acecopro-100 improves lung function and enhances patients’ quality of life. It is an essential part of treatment plans for individuals suffering from chronic respiratory conditions, making it a trusted choice among physicians.