AVEBRIM

Avebrim E&E Drops

Avebrim E&E Drops is an advanced ophthalmic formulation specially designed to reduce elevated intraocular pressure (IOP) and provide effective relief in patients suffering from open-angle glaucoma or ocular hypertension. The combination of Brimonidine Tartrate 0.1% and Benzalkonium Chloride 0.005% offers a dual mechanism of action—lowering fluid production and enhancing fluid outflow from the eyes—thereby helping maintain optimal eye pressure and protect vision over the long term.

Brimonidine Tartrate 0.1%, the main active ingredient, is a highly selective alpha-2 adrenergic receptor agonist. It works primarily by decreasing the production of aqueous humor (the fluid within the eye) and simultaneously increasing uveoscleral outflow. This balanced approach helps reduce intraocular pressure, a major risk factor for optic nerve damage and vision loss associated with glaucoma. Brimonidine has been clinically proven to be both effective and well-tolerated, offering sustained control of IOP without significantly affecting pupil size or visual clarity.

Benzalkonium Chloride 0.005%, a mild preservative, ensures the sterility and stability of the solution, preventing microbial contamination during storage and use. While it acts as a preservative, it is used in a minimal and ophthalmologically safe concentration to ensure maximum patient comfort and safety. The solution is formulated to be gentle on the ocular surface, making it suitable for long-term therapy under medical supervision.

Avebrim E&E Drops is presented as a clear, sterile, aqueous solution intended for topical ophthalmic use. It is recommended for patients diagnosed with open-angle glaucoma or ocular hypertension who require effective and sustained reduction of intraocular pressure. By maintaining normal pressure within the eye, Avebrim helps prevent progressive optic nerve damage and irreversible vision loss.

Key Benefits:

• Effectively lowers intraocular pressure in glaucoma and ocular hypertension.

• Provides dual action—reduces aqueous humor production and increases outflow.

• Well-tolerated for long-term use with minimal systemic absorption.

• Gentle formulation suitable for sensitive eyes.

• Helps protect the optic nerve and preserve vision.

Directions for Use:
Instill one drop in the affected eye(s) as directed by the ophthalmologist, typically two to three times daily. To prevent contamination, avoid touching the dropper tip to any surface or to the eye itself. Wait at least five minutes before using any other ophthalmic medication.

Precautions:

• For external use only.

• Avoid contact lenses during administration and wait at least 15 minutes before reinsertion.

• Use with caution in patients with severe cardiovascular disease, depression, or vascular disorders.

• Store in a cool, dry place away from direct sunlight.

• Keep out of reach of children.

Conclusion:
Avebrim E&E Drops represents a trusted and effective therapeutic choice for managing ocular hypertension and glaucoma. Its clinically proven combination of Brimonidine Tartrate 0.1% and Benzalkonium Chloride 0.005% ensures optimal IOP control, ocular comfort, and long-term protection of visual health. With consistent use as prescribed, Avebrim helps maintain clear vision and eye wellness for years to come.