Product Details-
| Composition | Levetiracetam – 750 mg |
|---|---|
| Dosage | TABLET |
| Packing Size | 10×10 |
| Packing | Alu-Alu |
Levicip 750 is a high-strength pharmaceutical formulation containing 750 mg of levetiracetam, a widely prescribed antiepileptic drug (AED) known for its efficacy and safety in managing various seizure disorders. Levicip 750 plays a crucial role in controlling partial-onset seizures, generalized seizures, and neuropathic pain conditions, helping patients achieve better seizure control and improved quality of life.
This comprehensive guide covers Levicip 750’s pharmacology, mechanism of action, therapeutic uses, dosing guidelines, safety profile, drug interactions, and patient experiences, providing an essential resource for patients, caregivers, and healthcare professionals involved in epilepsy and neurological care.
Each tablet of Levicip 750 contains 750 mg of levetiracetam, a pyrrolidine derivative that exhibits broad-spectrum anticonvulsant activity. The formulation is designed to ensure high bioavailability and consistent plasma levels, essential for maintaining seizure control throughout the day.
Levicip 750 tablets include inert excipients that enhance stability and absorption, minimizing gastrointestinal irritation and enhancing patient compliance.
Levicip 750’s active ingredient, levetiracetam, operates through a unique mechanism that differentiates it from traditional antiepileptic drugs. It binds selectively to synaptic vesicle protein 2A (SV2A) in the brain, modulating neurotransmitter release and reducing neuronal hyperexcitability.
By regulating synaptic vesicle exocytosis, Levicip 750 stabilizes neuronal circuits and prevents abnormal electrical discharges responsible for seizures. This mechanism provides effective seizure control with a low risk of drug interactions and side effects.
Levicip 750 is indicated for:
Partial-onset Seizures: As monotherapy or adjunctive therapy in adults and children aged 4 years and older.
Generalized Tonic-Clonic Seizures: For managing idiopathic generalized epilepsy.
Myoclonic Seizures: Especially in juvenile myoclonic epilepsy.
Neuropathic Pain: Off-label use for conditions like diabetic neuropathy and postherpetic neuralgia.
Other Neurological Disorders: In certain cases, for mood stabilization or off-label neurological applications.
This versatility makes Levicip 750 a preferred choice for complex epilepsy management.
Levicip 750 is administered orally, typically in divided doses twice daily. Key dosing guidelines include:
Initial Dose: Usually starts at 500 mg twice daily for adults, with adjustment based on clinical response.
Maintenance Dose: Can be titrated up to 1500 mg twice daily, depending on seizure control and tolerability.
Pediatric Dosing: Adjusted according to body weight and age, with close monitoring.
Dose Adjustments: Necessary in patients with renal impairment or elderly patients.
Discontinuation: Should be gradual to avoid precipitating withdrawal seizures.
Adherence to prescribed dosing schedules is critical for seizure prevention.
Patients treated with Levicip 750 commonly experience:
Effective Seizure Reduction: Significant decrease in frequency and severity of partial and generalized seizures.
Improved Neuropathic Pain Relief: Reduction in chronic nerve pain symptoms.
Minimal Cognitive Side Effects: Unlike some AEDs, levetiracetam has minimal impact on cognition and alertness.
Favorable Safety Profile: Low incidence of serious adverse events encourages long-term adherence.
Improved Sleep Patterns: Seizure control often leads to better sleep quality and daytime functioning.
These benefits contribute to enhanced daily living and patient independence.
Levicip 750 is generally well tolerated; however, some side effects may occur:
Common Side Effects: Fatigue, dizziness, headache, irritability, and somnolence.
Behavioral Changes: Mood swings, agitation, or depression in some patients, requiring monitoring.
Gastrointestinal Symptoms: Nausea, vomiting, and diarrhea, often mild and transient.
Allergic Reactions: Rash or hypersensitivity, though rare.
Most side effects diminish with continued use or dosage adjustment.
Although rare, serious adverse events can include:
Severe Behavioral Symptoms: Suicidal ideation or psychosis requiring immediate medical attention.
Hypersensitivity Reactions: Stevens-Johnson syndrome or toxic epidermal necrolysis, extremely rare but serious.
Hematologic Effects: Rare cases of thrombocytopenia or leukopenia.
Renal Impairment: Dose adjustments required in renal dysfunction.
Patients should report unusual symptoms promptly for evaluation.
Levicip 750 is contraindicated in patients with:
Known hypersensitivity to levetiracetam or any tablet components.
Severe renal impairment without appropriate dose modification.
Use caution in patients with:
Psychiatric disorders, due to potential mood-related side effects.
Pregnant or breastfeeding women; use only if benefits outweigh risks.
Regular monitoring ensures safe therapy.
Levicip 750 has a low potential for drug interactions but requires caution with:
Other Antiepileptic Drugs: Dosage adjustments may be necessary to avoid additive side effects.
CNS Depressants: Alcohol or benzodiazepines may enhance sedative effects.
Hormonal Contraceptives: May slightly reduce efficacy; alternative contraception advised.
Renally Excreted Drugs: Monitor for altered clearance.
Full disclosure of all medications to healthcare providers is essential.
For optimal benefits, Levicip 750 should be combined with:
Regular Neurological Assessments: Monitoring seizure frequency and side effects.
Healthy Lifestyle: Balanced diet, regular exercise, and stress management.
Adequate Sleep Hygiene: To reduce seizure triggers.
Psychological Support: Counseling for behavioral side effects or mood disorders.
Avoidance of Triggers: Such as alcohol, sleep deprivation, and stress.
Such holistic care improves long-term control.
Store Levicip 750 tablets in a cool, dry place away from direct sunlight, heat, and moisture. Maintain storage temperature between 20°C and 25°C. Keep medication out of reach of children and pets. Dispose of expired or unused medication responsibly.
How soon does Levicip 750 start working?
Initial seizure control is often seen within the first week; full benefits develop over several weeks.
Is Levicip 750 addictive?
No, levetiracetam is not addictive but requires consistent use to maintain control.
Can I drink alcohol while taking Levicip 750?
Alcohol may increase sedation and seizure risk; it is best avoided.
What if I miss a dose?
Take it as soon as remembered unless close to the next dose; do not double doses.
Is Levicip 750 safe during pregnancy?
Only if prescribed by a healthcare provider; risks and benefits must be evaluated.
Levicip 750 is a highly effective and well-tolerated medication for managing a broad spectrum of seizure disorders and neuropathic pain conditions. Its unique mechanism of action targeting synaptic vesicle proteins offers potent seizure control with minimal drug interactions and side effects.
When combined with comprehensive medical care, lifestyle management, and patient education, Levicip 750 empowers individuals to regain control over their neurological health, improving daily functioning, safety, and quality of life.
