S AMINE 2.5

S AMINE 2.5 Tablets

Description:

S AMINE 2.5 is a highly effective antihypertensive medication formulated with S(-)Amlodipine 2.5 mg, the active enantiomer of amlodipine. This innovative formulation ensures greater potency at a lower dose and offers better safety and tolerability compared to conventional racemic amlodipine. It is primarily prescribed to manage high blood pressure (hypertension) and certain types of angina (chest pain), helping to prevent cardiovascular complications such as heart attack, stroke, and kidney damage.

S(-)Amlodipine works by blocking calcium influx into vascular smooth muscle and cardiac muscle cells, leading to vasodilation (widening of blood vessels), reduced vascular resistance, and improved blood flow. By relaxing blood vessels, it effectively lowers blood pressure and decreases the workload on the heart.

Key Benefits:

✅ High Potency at Low Dose – S(-)Amlodipine is the active isomer, offering better efficacy at a lower dose.
✅ Improved Tolerability – Lower risk of side effects like ankle edema and palpitations compared to conventional amlodipine.
✅ Long-Lasting Control – Provides 24-hour blood pressure control with a once-daily dose.
✅ Heart Protection – Reduces cardiovascular strain, lowering the risk of stroke and heart attack.
✅ Smooth Blood Pressure Reduction – Gradual and consistent BP lowering without sudden drops.

Mechanism of Action:

S(-)Amlodipine is a calcium channel blocker (CCB) of the dihydropyridine class. It selectively inhibits L-type calcium channels in vascular smooth muscle, preventing calcium entry. This results in vasodilation, reduced peripheral vascular resistance, and decreased blood pressure.

Indications:

S AMINE 2.5 is prescribed for:

• Essential hypertension (primary high blood pressure)

• Stable angina pectoris

• Vasospastic (Prinzmetal’s) angina

• Prevention of cardiovascular events in patients at risk

Dosage & Administration:

• Typical starting dose: 2.5 mg once daily

• Dosage may be adjusted as per physician’s guidance.

• Can be taken with or without food.

• Should be taken at the same time each day for maximum benefit.

Safety and Precautions:

• Monitor blood pressure and heart rate regularly.

• Use with caution in patients with severe liver impairment or heart failure.

• Pregnant and breastfeeding women should take only under medical supervision.

• Avoid sudden discontinuation; taper off under a doctor’s guidance.

Possible Side Effects:

Most patients tolerate S AMINE 2.5 well. Common side effects may include:

• Mild headache

• Flushing

• Dizziness

• Fatigue

• Peripheral edema (rare with this formulation)

Seek medical help immediately in case of severe allergic reactions or extreme dizziness.

Why Choose S AMINE 2.5?

S AMINE 2.5 offers precision therapy for hypertension with lower side effects and superior clinical outcomes. Its enantiomeric purity ensures targeted efficacy, making it an excellent choice for long-term hypertension management.